Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.47 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25455155 | 0.86 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2RAB9AHTT | |
| SCHEMBL11870719 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2RAB9AHTT | |
| SCHEMBL23817955 | 0.80 | SMN1; SMN2 (0.60) | ALDH1A1LMNASMN1; SMN2RAB9AHTT | |
| SCHEMBL23818000 | 0.79 | ALDH1A1 (0.72) | ALDH1A1LMNASMN1; SMN2RAB9AHTT | |
| SCHEMBL23818002 | 0.77 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2RAB9AHTT | |
| SCHEMBL23817999 | 0.72 | ALDH1A1 (0.74) | ALDH1A1LMNASMN1; SMN2RAB9AHTT | |
| SCHEMBL23818006 | 0.70 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2RAB9AHTT | |
| SCHEMBL23723512 | 0.70 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2RAB9AHTT | |
| SCHEMBL7768212 | 0.70 | ALDH1A1 (0.61) | ALDH1A1LMNASMN1; SMN2RAB9AHTT | |
| SCHEMBL23818005 | 0.69 | ALDH1A1 (0.69) | ALDH1A1LMNASMN1; SMN2RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
| WO-2021183431-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | FEM1B, GSKIP, FNIP1 | ALDH1A1 4563/4885LMNA 1940/4885SMN1; SMN2 2172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.