SCHEMBL238214

SCHEMBL238214

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCCN)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)[C@@H](C)O)C(C)C)[C@@H](C)O

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPY2R P49146 8/20 0.69
NPY4R P50391 8/20 0.69
NPY5R Q15761 8/20 0.69
NPY1R P25929 6/20 0.69
TFPI P10646 4/20 0.69
RAMP3 O60896 3/20 0.68
CALCR P30988 3/20 0.68
RAMP1 O60894 1/20 0.68
RAMP2 O60895 1/20 0.68
CALCRL Q16602 1/20 0.68
GLP1R P43220 2/20 0.66
CXCR4 P61073 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2905167 0.94 CALCR (0.76) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL29720295 0.92 CALCR (0.73) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL4331434 0.91 NPY2R (0.75) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL15669203 0.90 NPY2R (0.74) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL9979655 0.89 NPY2R (0.69) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30299016 0.89 CALCR (0.69) RAMP3CALCRRAMP1RAMP2CALCRL
SCHEMBL29519841 0.88 CALCR (0.71) RAMP3CALCRRAMP1RAMP2CALCRL
SCHEMBL15669269 0.88 NPY2R (0.76) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30574250 0.88 NPY2R (0.72) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29436010 0.88 NPY2R (0.77) NPY2RNPY4RNPY5RNPY1RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3667 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031677-A Leptin receptor agonist antibodies for the treatment of metabolic dysfunction or hypoleptinemia 瑞泽恩制药公司 2026-05-15 CN claimed
CN-122005762-A Tenipotene oral self-emulsifying preparation and preparation method thereof 深圳翰宇药业股份有限公司 2026-05-12 CN claimed
EP-4734978-A2 COMBINATION THERAPIES USING PSILOCYBIN University of Padova (IT) 2026-05-06 EP claimed
WO-2026090520-A1 METHOD OF PREVENTING MUSCLE LOSS BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2026-04-30 WO claimed
EP-3532092-B1 IMMUNOGLOBULINS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2026-04-29 EP claimed
US-12605354-B2 Azelaic acid esters in the treatment or prevention of dyslipidemia and associated conditions NEW FRONTIER LABS, LLC (US) 2026-04-21 US claimed
US-20260102473-A1 NOVEL FORMULATIONS ARECOR LTD (GB) 2026-04-16 US claimed
EP-4074729-B1 AMYLIN ANALOGUES ZEALAND PHARMA AS (DK) 2026-04-15 EP claimed
US-20260091086-A1 POLYPEPTIDE COMBINATIONS AND USES THEREOF MEDIMMUNE LTD (GB) 2026-04-02 US claimed
US-20260085061-A1 PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS SITRYX THERAPEUTICS LIMITED (GB) 2026-03-26 US claimed
WO-2022066212-A1 A LONG-LASTING GLP1 ANALOGUE DRUG FOR TYPE-2 DIABETES WEI YANG (US) 2022-03-31 WO claimed
WO-2022060827-A2 USE OF LEPR AGONISTS FOR PAIN REGENERON PHARMACEUTICALS, INC. (US) 2022-03-24 WO claimed
EP-3411026-B1 USE OF STIMULATORS OF SOLUBLE GUANYLATE CYCLASE FOR THE TREATMENT OF NONALCOHOLIC STEATOHEPATITIS (NASH) CYCLERION THERAPEUTICS INC (US) 2022-03-09 EP claimed
CN-107921094-B IGFBP3 and uses thereof 圣拉斐尔医院有限公司 2022-03-01 CN claimed
CN-114127105-A Anti-metallothionein antibodies and uses thereof 康涅狄格大学 2022-03-01 CN claimed
WO-2022040035-A1 TREATMENT OF OBESITY IN SUBJECTS HAVING VARIANT NUCLEIC ACID MOLECULES ENCODING CALCITONIN RECEPTOR (CALCR) REGENERON PHARMACEUTICALS, INC. (US) 2022-02-24 WO claimed
EP-3658115-B1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AT LEAST HUMAN INSULIN A21G AND A PRANDIAL ACTION GLUCAGON SUPPRESSOR ADOCIA (FR) 2022-02-23 EP claimed
EP-3955913-A1 COMPOSITIONS AND METHODS FOR TREATING DIABETES ENZYCHEM LIFESCIENCES (KR) 2022-02-23 EP claimed
EP-3956259-A1 CO-FORMULATIONS OF AMYLIN ANALOGUES WITH INSULIN ANALOGUES FOR TREATMENT OF DIABETES The Board Of Trustees Of The Leland Stanford Junior University (US) 2022-02-23 EP claimed
CN-114026107-A Production of disulfide peptides 巴克姆股份公司 2022-02-08 CN claimed