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Sugi Predict / Compounds / SCHEMBL29436010

SCHEMBL29436010

SCHEMBL29436010

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O

nearest known ligand 0.77

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 9/20 0.77
▸ NPY4R P50391 8/20 0.77
▸ NPY5R Q15761 8/20 0.77
▸ NPY1R P25929 7/20 0.77
▸ TFPI P10646 4/20 0.72
▸ RAMP3 O60896 1/20 0.72
▸ CALCR P30988 1/20 0.72
▸ GLP1R P43220 5/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30735721 1.00 NPY2R (0.77) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29411681 0.96 NPY2R (0.72) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29399759 0.90 NPY2R (0.89) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL4331434 0.90 NPY2R (0.75) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL15669203 0.90 NPY2R (0.74) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30423064 0.90 KEAP1 (0.69) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30397368 0.89 NPY2R (0.82) NPY2RNPY4RNPY5RNPY1RTFPI
Neuropeptide-Y SCHEMBL3051623 0.89 NPY2R (0.82) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30432021 0.89 NPY2R (0.68) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29357353 0.88 NPY2R (0.73) NPY2RNPY4RNPY5RNPY1RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111197024-B Pancreatic-like structure, construction method and application thereof 杭州捷诺飞生物科技股份有限公司 2023-08-18 — — CN claimed
US-20260077076-A1 AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO TAGWORKS PHARMACEUTICALS B.V. (NL) 2026-03-19 — — US disclosed
US-12558378-B2 Methods for lowering blood glucose JANSSEN BIOTECH, INC. (US) 2026-02-24 — — US disclosed
US-20250127793-A1 CONJUGATES OF SURROGATE LIGHT CHAIN CONSTRUCTS REVOPSIS HOLDINGS, LLC 2025-04-24 — — US disclosed
EP-3983020-B9 AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO TAGWORKS PHARMACEUTICALS B V (NL) 2024-10-16 — — EP disclosed
EP-4438720-A2 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS Janssen Biotech, Inc. (US) 2024-10-02 — — EP disclosed
EP-4424713-A2 AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO Tagworks Pharmaceuticals B.V. (NL) 2024-09-04 — — EP disclosed
EP-3527658-B1 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS JANSSEN BIOTECH INC (US) 2024-07-24 — — EP disclosed
EP-3983020-B1 AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO TAGWORKS PHARMACEUTICALS B V (NL) 2024-06-26 — — EP disclosed
US-11890304-B2 Pancreatic endocrine cells and methods thereof JANSSEN BIOTECH, INC. (US) 2024-02-06 — — US disclosed
CN-111197024-B Pancreatic-like structure, construction method and application thereof 杭州捷诺飞生物科技股份有限公司 2023-08-18 — — CN disclosed
US-11708562-B2 Differentiation of human embryonic stem cells JANSSEN BIOTECH, INC. (US) 2023-07-25 — — US disclosed
US-11505783-B2 Differentiation of human embryonic stem cells JANSSEN BIOTECH, INC. (US) 2022-11-22 — — US disclosed
US-20220331458-A1 AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO TAGWORKS PHARMACEUTICALS B.V. (NL) 2022-10-20 — — US disclosed
US-20220296653-A1 METHODS FOR LOWERING BLOOD GLUCOSE JANSSEN BIOTECH, INC. (US) 2022-09-22 — — US disclosed
US-11369642-B2 Methods for lowering blood glucose JANSSEN BIOTECH, INC. (US) 2022-06-28 — — US disclosed
CN-114599645-A Reagents for cleaving a label from a biomolecule in vivo 泰克沃尔科斯制药有限公司 2022-06-07 — — CN disclosed
EP-3983020-A1 AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO Tagworks Pharmaceuticals B.V. (NL) 2022-04-20 — — EP disclosed
EP-3981415-A1 TREATMENT OF DIABETES WITH PANCREATIC ENDOCRINE PRECURSOR CELLS Janssen Biotech, Inc. (US) 2022-04-13 — — EP disclosed
EP-3957716-A1 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS Janssen Biotech, Inc. (US) 2022-02-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260077076-A1 AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO FCGR3B, MSR1, FCGR2A NPY2R 539/4885NPY4R 820/4885NPY5R 506/4885
US-12558378-B2 Methods for lowering blood glucose PAX2, PROX1, TCF4 NPY2R 488/4885NPY4R 108/4885NPY5R 341/4885
US-20220331458-A1 AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO DNASE1L3, CTSE, DCLRE1B NPY2R 3773/4885NPY4R 4209/4885NPY5R 3350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.