SCHEMBL2382567

SCHEMBL2382567

CC(C)(C)OC(=O)C1(C(F)(F)F)CC2C=CC1C2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13520497 0.85
SCHEMBL14567551 0.85 CYP2C19 (0.33) CYP2D6CYP2C19
SCHEMBL13525789 0.80 CYP2C19 (0.35) CYP2D6CYP2C19
SCHEMBL13525991 0.79 CYP2D6 (0.33) CYP2D6CYP2C19
SCHEMBL13520499 0.79
SCHEMBL16894040 0.78 CYP2D6 (0.34) CYP2D6CYP2C19
SCHEMBL13744776 0.78 HTT (0.32) CYP2D6CYP2C19
SCHEMBL13744383 0.78 ABHD6 (0.32)
SCHEMBL23694120 0.78 CYP2C19 (0.33) CYP2D6CYP2C19
SCHEMBL75012 0.78 CYP2C19 (0.33) CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1415974-B1 PROCESS FOR PRODUCTION OF FLUORINE-CONTAINING NORBORNENE DERIVATIVES DAIKIN IND LTD (JP) 2017-03-01 EP disclosed
EP-1762895-B1 Antireflective Hard Mask Compositions ROHM & HAAS ELECT MAT (US) 2016-02-24 EP disclosed
US-8373241-B2 Antireflective hard mask compositions ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2013-02-12 US disclosed
US-8026037-B2 Si-polymers and photoresists comprising same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2011-09-27 US disclosed
US-8026037-B2 Si-polymers and photoresists comprising same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2011-09-27 US disclosed
US-20100297539-A1 ANTIREFLECTIVE HARD MASK COMPOSITIONS ROHM AND HAAS ELECTRONIC MATERIALS, L.L.C. (US) 2010-11-25 US disclosed
US-7649118-B2 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. (JP) 2010-01-19 US disclosed
US-7649118-B2 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. (JP) 2010-01-19 US disclosed
US-7605439-B2 Antireflective hard mask compositions ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2009-10-20 US disclosed
US-20090136867-A1 Si-polymers and photoresists comprising same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2009-05-28 US disclosed
EP-1762895-A1 Antireflective Hard Mask Compositions Rohm and Haas Electronic Materials, L.L.C. (US) 2007-03-14 EP disclosed
US-7186773-B2 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-7186773-B2 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-7108955-B2 Polysiloxane, process for production thereof and radiation-sensitive resin composition JSR CORPORATION (JP) 2006-09-19 US disclosed
US-20060058480-A1 Polymerizable monomer polymeric compound resin compositions for photoresist and method for producing semiconductor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-03-16 US disclosed
US-20050282985-A1 FLUORINE-ATOM-CONTAINING POLYMERIZABLE UNSATURATED-MONOMER, FLUORINE-ATOM-CONTAINING POLYMERIC COMPOUND AND PHOTORESIST RESIN COMPOSITION DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2005-12-22 US disclosed
US-20040248032-A1 Polymers and photoresists comprising same ROHM AND HAAS ELECTRONIC MATERIALS, L.L.C. 2004-12-09 US disclosed
EP-1455230-A2 Polymers and photoresists comprising same Rohm and Haas Electronic Materials, L.L.C. (US) 2004-09-08 EP disclosed
US-20040143082-A1 Polysiloxane, process for production thereof and radiation-sensitive resin composition JSR CORPORATION (JP) 2004-07-22 US disclosed
EP-1398339-A1 POLYSILOXANE, PROCESS FOR PRODUCTION THEREOF AND RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2004-03-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050282985-A1 FLUORINE-ATOM-CONTAINING POLYMERIZABLE UNSATURATED-MONOMER, FLUORINE-ATOM-CONTAINING POLYMERIC COMPOUND AND PHOTORESIST RESIN COMPOSITION AFF1, AFF2, FPR1 CYP2D6 3399/4885CYP2C19 2474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.