Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23827459 | 0.97 | GRM6 (0.52) | GRM6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23827463 | 0.96 | GRM6 (0.51) | GRM6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23827453 | 0.91 | GRM6 (0.55) | GRM6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23827448 | 0.84 | SIGMAR1 (0.45) | GRM6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23827437 | 0.79 | GRM6 (0.43) | GRM6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2655161 | 0.77 | ALDH1A1 (0.43) | GRM6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23827462 | 0.76 | GRM6 (0.45) | GRM6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23827450 | 0.73 | ALDH1A1 (0.43) | GRM6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23827478 | 0.73 | COPS5 (0.45) | GRM6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1621985 | 0.71 | ALDH1A1 (0.49) | GRM6ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864312-B1 | NOVEL ANTI-CANCER THIOPHENE COMPOUNDS | UNIV LEUVEN KATH (BE) | 2021-09-22 | — | — | EP | claimed |
| EP-2864312-B1 | NOVEL ANTI-CANCER THIOPHENE COMPOUNDS | UNIV LEUVEN KATH (BE) | 2021-09-22 | — | — | EP | disclosed |