Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.32 |
| ▸ | BPTF | Q12830 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23827445 | 0.77 | GRM6 (0.52) | ALDH1A1HSD17B10MAPK1TSHRGRM6 | |
| SCHEMBL23827459 | 0.77 | GRM6 (0.52) | ALDH1A1HSD17B10MAPK1TSHRGRM6 | |
| SCHEMBL1621985 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HSD17B10MAPK1TSHRGRM6 | |
| SCHEMBL23827463 | 0.76 | GRM6 (0.51) | ALDH1A1HSD17B10MAPK1TSHRGRM6 | |
| SCHEMBL1622057 | 0.75 | ADORA2A (0.48) | ALDH1A1HSD17B10MAPK1TSHRGRM6 | |
| SCHEMBL23827453 | 0.73 | GRM6 (0.55) | ALDH1A1HSD17B10MAPK1TSHRGRM6 | |
| SCHEMBL23827448 | 0.71 | SIGMAR1 (0.45) | ALDH1A1HSD17B10MAPK1TSHRGRM6 | |
| SCHEMBL23827437 | 0.71 | GRM6 (0.43) | ALDH1A1HSD17B10MAPK1TSHRGRM6 | |
| SCHEMBL641581 | 0.68 | GRM6 (0.52) | ALDH1A1HSD17B10MAPK1TSHRGRM6 | |
| SCHEMBL23827462 | 0.67 | GRM6 (0.45) | ALDH1A1GRM6ADORA2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807411-A1 | CYANOTHIOPHENES, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-07-18 | — | — | EP | disclosed |
| US-20060094764-A1 | Cyanothiophenes, their preparation and their use in pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-04 | — | — | US | disclosed |
| WO-2006042850-A1 | CYANOTHIOPHENES, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094764-A1 | Cyanothiophenes, their preparation and their use in pharmaceutical compositions | GLRB, GPR6, GRM3 | ALDH1A1 3592/4885HSD17B10 1078/4885MAPK1 4252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.