SCHEMBL23828846

SCHEMBL23828846

Cc1ccc(C(=O)C(=O)c2ccccc2)c(N(C)C)c1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 9/20 0.55
CES1 P23141 7/20 0.55
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.41
POLB P06746 1/20 0.41
EGFR P00533 1/20 0.39
NPC1 O15118 1/20 0.39
PKM P14618 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23828848 0.84 RAB9A (0.64) CES2CES1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL375035 0.81 ALDH1A1 (0.62) CES2CES1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL23828850 0.80 CES2 (0.58) CES2CES1RAB9ASMN1; SMN2ALDH1A1
Hydrochloric Acid SCHEMBL9403739 0.80 ALDH1A1 (0.60) CES2CES1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL27905649 0.80 CES2 (0.68) CES2CES1RAB9ASMN1; SMN2NPC1
SCHEMBL2420457 0.79 CSNK2A1 (0.52) SMN1; SMN2ALDH1A1TP53GAAMAPT
SCHEMBL10946702 0.78 RAB9A (0.47) CES2CES1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL7596950 0.75 C5AR1 (0.53) RAB9ASMN1; SMN2ALDH1A1TP53GAA
SCHEMBL17326808 0.74 ALDH1A1 (0.40) RAB9ASMN1; SMN2ALDH1A1TP53GAA
SCHEMBL2157002 0.72 CES2 (1.00) CES2CES1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210292472-A1 Photosensitive Resin Composition NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2021-09-23 US disclosed