Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 5/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23830981 | 0.80 | KMT2A (0.57) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL23830536 | 0.77 | KMT2A (0.54) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL23830479 | 0.74 | KDM4E (0.48) | KMT2ANPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL23331245 | 0.74 | P2RX7 (0.40) | KMT2AMEN1ALPLPOLBNPC1 | |
| SCHEMBL23331244 | 0.72 | P2RX7 (0.43) | KMT2AMEN1ALPLPOLBNPC1 | |
| SCHEMBL22866360 | 0.71 | KMT2A (0.97) | KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL23830465 | 0.71 | HDAC1 (0.47) | KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL5980561 | 0.71 | EPHX2 (0.39) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13550224 | 0.70 | ALDH1A1 (0.56) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL657615 | 0.70 | KMT2A (1.00) | KMT2AMEN1GAAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292305-A1 | Cyclic Ureas | SIRONAX LTD (KY) | 2021-09-23 | — | — | US | disclosed |
| US-20210292305-A1 | Cyclic Ureas | SIRONAX LTD (KY) | 2021-09-23 | — | — | US | disclosed |
| CN-113302183-A | Cyclic ureas | 圣瑞诺有限公司 | 2021-08-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292305-A1 | Cyclic Ureas | RIPK1, RIPK3, RIPK4 | KMT2A 4226/4885MEN1 3182/4885ALPL 4102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.