Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL23830763

N#Cc1ccc(OC2CNC2)c(F)c1.O=C(O)C(F)(F)F

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GPR6 P46095 6/20 0.51
PDE9A O76083 1/20 0.44
USP30 Q70CQ3 1/20 0.43
SLC6A4 P31645 2/20 0.41
BCL9 O00512 2/20 0.41
CTNNB1 P35222 2/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23842656 0.88 SLC6A4 (0.48) USP30SLC6A4
Trifluoroacetic Acid SCHEMBL23830477 0.83 GPR6 (0.47) GPR6SLC6A4
Trifluoroacetic Acid SCHEMBL23830498 0.81 EPHX2 (0.46)
Trifluoroacetic Acid SCHEMBL23850944 0.81 PDE9A (0.44) GPR6PDE9ASLC6A4
Trifluoroacetic Acid SCHEMBL23830454 0.79 SLC6A4 (0.51) SLC6A4
Trifluoroacetic Acid SCHEMBL21590502 0.78 SLC6A2 (0.61) SLC6A4
Trifluoroacetic Acid SCHEMBL23830576 0.77 MGLL (0.40) SLC6A4BCL9CTNNB1
SCHEMBL225826 0.76 SLC6A2 (0.49) GPR6USP30SLC6A4BCL9CTNNB1
Trifluoroacetic Acid SCHEMBL23854128 0.76 GPR6 (0.46) GPR6PDE9ASLC6A4
Trifluoroacetic Acid SCHEMBL23830676 0.76 PGR (0.41) SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210292305-A1 Cyclic Ureas SIRONAX LTD (KY) 2021-09-23 US disclosed
CN-113302183-A Cyclic ureas 圣瑞诺有限公司 2021-08-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210292305-A1 Cyclic Ureas RIPK1, RIPK3, RIPK4 GPR6 2812/4885PDE9A 1593/4885USP30 221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.