Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199419 | 1.00 | CYP2A6 (0.43) | CYP2A6FLT3AGXTMAPTLMNA | |
| SCHEMBL30439601 | 0.96 | CYP2A6 (0.45) | CYP2A6FLT3AGXTMAPTLMNA | |
| SCHEMBL23832432 | 0.96 | CYP2A6 (0.45) | CYP2A6FLT3AGXTMAPTLMNA | |
| SCHEMBL14926619 | 0.83 | KDM4E (0.47) | CYP2A6MAPTHTTKDM4EMAPK1 | |
| SCHEMBL812098 | 0.81 | MAOB (0.44) | CYP1A2KMT2AMEN1PTGS2 | |
| SCHEMBL29936898 | 0.80 | CYP1A2 (0.59) | CYP2A6AGXTMAPTLMNAHTT | |
| SCHEMBL1961527 | 0.80 | CYP1A2 (0.59) | CYP2A6AGXTMAPTLMNAHTT | |
| SCHEMBL2171086 | 0.80 | KMT2A (0.53) | CYP2A6MAPTLMNAHTTCYP1A2 | |
| SCHEMBL12454839 | 0.80 | NQO1 (0.52) | MAPTCYP1A2KDM4EMAPK1TDP1 | |
| SCHEMBL700133 | 0.78 | WDR5 (0.51) | LMNAHTTKDM4EMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150929-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | UNIV TEXAS (US) | 2023-05-18 | — | — | US | disclosed |
| CN-116134015-A | Selective acyclic nucleotide activating factor for CAMP sensor EPAC1 | 得克萨斯州大学系统董事会 | 2023-05-16 | — | — | CN | disclosed |
| EP-4121411-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021188728-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150929-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | CREB1, RAPGEF4, ATF4 | CYP2A6 3695/4885FLT3 4208/4885AGXT 4567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.