Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 7/20 | 0.48 |
| ▸ | CES2 | O00748 | 6/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TAS2R10 | Q9NYW0 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL31683012 | 0.90 | CA2 (0.64) | CA2CA4CES1CES2ALPL | |
| Benzoic Acid SCHEMBL31683168 | 0.89 | CA2 (0.53) | CA2CA4CES1CES2ALPL | |
| Benzoic Acid SCHEMBL31683104 | 0.88 | CA2 (0.61) | CA2CA4CES1CES2ALPL | |
| Isophthalic Acid SCHEMBL3412411 | 0.86 | CA2 (0.43) | CA2CA4CES1CES2ALPL | |
| Tetrylammonium SCHEMBL112480 | 0.86 | CA2 (0.64) | CA2CA4CES1CES2MEN1 | |
| Benzoic Acid SCHEMBL108980 | 0.85 | CA2 (0.76) | CA2CA4CES1CES2POLB | |
| Isophthalic Acid SCHEMBL3412414 | 0.84 | NOS3 (0.46) | CA2CA4KMT2AHPGDSMN1; SMN2 | |
| Benzoic Acid SCHEMBL9012680 | 0.83 | TSHR (0.61) | CA2CES1CES2MEN1LMNA | |
| Benzoic Acid SCHEMBL158696 | 0.83 | CA2 (0.80) | CA2CA4CES1CES2POLB | |
| Tetrylammonium SCHEMBL28390101 | 0.82 | CA2 (0.59) | CA2CA4CES1CES2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330311-B1 | STORAGE STABLE 1K-POLYURETHANE-PREPREGS AND MOULDED ARTICLE MADE FROM SAME ON THE BASIS OF A POLYURETHANE COMPOSITION | EVONIK OPERATIONS GMBH (DE) | 2021-05-05 | — | — | EP | claimed |
| US-10633519-B2 | Storage-stable polyurethane prepregs and mouldings produced therefrom composed of a polyurethane composition with liquid resin components | EVONIK OPERATIONS GMBH (DE) | 2020-04-28 | — | — | US | claimed |
| US-10626236-B2 | Storage-stable one-component polyurethane prepregs and shaped bodies composed of polyurethane composition that have been produced therefrom | EVONIK OPERATIONS GMBH (DE) | 2020-04-21 | — | — | US | claimed |
| US-20180155515-A1 | STORAGE-STABLE ONE-COMPONENT POLYURETHANE PREPREGS AND SHAPED BODIES COMPOSED OF POLYURETHANE COMPOSITION THAT HAVE BEEN PRODUCED THEREFROM | EVONIK OPERATIONS GMBH (DE) | 2018-06-07 | — | — | US | claimed |
| EP-3330311-A1 | STORAGE STABLE 1K-POLYURETHANE-PREPREGS AND MOULDED ARTICLE MADE FROM SAME ON THE BASIS OF A POLYURETHANE COMPOSITION | Evonik Degussa GmbH (DE) | 2018-06-06 | — | — | EP | claimed |
| EP-2411439-B1 | PREPEGS AND MOLDED BODIES PRODUCED THEREOF AT LOW TEMPERATURE | EVONIK DEGUSSA GMBH (DE) | 2016-11-16 | — | — | EP | claimed |
| EP-2188320-B1 | DUAL CURE FORMULATIONS WITH COMPONENTS COMPRISING URETDIONE GROUPS | EVONIK DEGUSSA GMBH (DE) | 2014-05-14 | — | — | EP | claimed |
| US-20140087613-A1 | STORAGE-STABLE POLYURETHANE PREPREGS AND MOULDINGS PRODUCED THEREFROM COMPOSED OF A POLYURETHANE COMPOSITION WITH LIQUID RESIN COMPONENTS | EVONIK DEGUSSA GMBH (DE) | 2014-03-27 | — | — | US | claimed |
| EP-2688934-A1 | STORAGE-STABLE POLYURETHANE PREPREGS AND MOLDED PARTS PRODUCED THEREFROM MADE OF POLYURETHANE COMPOSITION HAVING LIQUID RESIN COMPONENTS | Evonik Degussa GmbH (DE) | 2014-01-29 | — | — | EP | claimed |
| US-8455090-B2 | Prepegs and molded bodies produced thereof at low temperature | EVONIK DEGUSSA GMBH (DE) | 2013-06-04 | — | — | US | claimed |
| WO-2012130672-A1 | STORAGE-STABLE POLYURETHANE PREPREGS AND MOLDED PARTS PRODUCED THEREFROM MADE OF POLYURETHANE COMPOSITION HAVING LIQUID RESIN COMPONENTS | EVONIK DEGUSSA GMBH (DE) | 2012-10-04 | — | — | WO | claimed |
| US-20120003890-A1 | PREPEGS AND MOLDED BODIES PRODUCED THEREOF AT LOW TEMPERATURE | EVONIK DEGUSSA GMBH (DE) | 2012-01-05 | — | — | US | claimed |
| US-20100227942-A1 | DUAL-CURE FORMULATIONS WITH COMPONENTS CONTAINING URETDIONE GROUPS | EVONIK DEGUSSA GMBH (DE) | 2010-09-09 | — | — | US | claimed |
| JP-8245493-A | — | — | None | — | — | JP | disclosed |
| US-20260071095-A1 | POLISHING COMPOSITION, POLISHING METHOD, AND METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE | FUJIMI INCORPORATED (JP) | 2026-03-12 | — | — | US | disclosed |
| US-20250320381-A1 | POLISHING COMPOSITION, POLISHING METHOD, AND METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE | FUJIMI INCORPORATED (JP) | 2025-10-16 | — | — | US | disclosed |
| JP-H08245493-A | COLD MOLTEN SALT | MITSUBISHI CHEM CORP | 1996-09-24 | — | — | JP | disclosed |
| EP-0543311-B1 | Electrolytic solution for electrolytic capacitor | NIPPON CHEMICON (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-5338472-A | Mixture of g-butyrolactone and ethylene glycol with quaternary alkylammonium phthalate, maleate or benzoate as solute, also with colloidal silica | NIPPON CHEMI-CON CORPORATION (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0543311-A2 | Electrolytic solution for electrolytic capacitor | NIPPON CHEMI-CON CORPORATION (JP) | 1993-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260071095-A1 | POLISHING COMPOSITION, POLISHING METHOD, AND METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE | PIEZO1, ZAP70, CAPN1 | CA2 695/4885CA4 634/4885CES1 3671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.