Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.80 |
| ▸ | CA4 | P22748 | 1/20 | 0.80 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 10/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL108980 | 0.92 | CA2 (0.76) | CA2CA4CES2CES1TSHR | |
| Benzoic Acid SCHEMBL3667327 | 0.92 | CA2 (0.84) | CA2CA4CES2CES1TSHR | |
| Benzoic Acid SCHEMBL11789341 | 0.92 | CA2 (0.94) | CA2CA4CES2CES1TSHR | |
| Benzoic Acid SCHEMBL5072459 | 0.90 | CA2 (0.80) | CA2CA4CES2CES1TSHR | |
| Benzoic Acid SCHEMBL27345977 | 0.90 | CA2 (0.90) | CA2CA4CES2CES1TSHR | |
| Benzoic Acid SCHEMBL28337190 | 0.90 | CA2 (0.80) | CA2CA4CES2CES1TSHR | |
| Benzoic Acid SCHEMBL11740323 | 0.90 | CA2 (0.80) | CA2CA4CES2CES1TSHR | |
| Benzoic Acid SCHEMBL457494 | 0.89 | CA2 (0.89) | CA2CA4CES2CES1TSHR | |
| Benzoic Acid SCHEMBL944537 | 0.89 | CA2 (0.89) | CA2CA4CES2CES1TSHR | |
| Benzoic Acid SCHEMBL20570232 | 0.89 | CA2 (0.89) | CA2CA4CES2CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060043-B1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CORTEVA AGRISCIENCE LLC (US) | 2025-11-26 | — | — | EP | claimed |
| EP-3578542-B1 | COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-11-12 | — | — | EP | claimed |
| EP-3578543-B1 | COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-08-20 | — | — | EP | claimed |
| EP-3578541-B1 | COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-05-28 | — | — | EP | claimed |
| US-20240188569-A1 | NEW YEAST STRAIN AND ITS USES FOR THE CONTROL OF PHYTOPATHOGENS | AGROVENTURES LLC (US) | 2024-06-13 | — | — | US | claimed |
| US-20240138408-A1 | COMPOSITION COMPRISING BENZYLAMINE ACARICIDE AND USE THEREOF | SHANGDONG KANGIAO BIO-TECHNOLOGY CO., LTD (CN) | 2024-05-02 | — | — | US | claimed |
| EP-4323496-A1 | NEW YEAST STRAIN AND ITS USES FOR THE CONTROL OF PHYTOPATHOGENS | AGROVENTURES S.R.L. (IT) | 2024-02-21 | — | — | EP | claimed |
| CN-117203324-A | Novel yeast strains and their use in controlling plant pathogens | 爱农创投有限公司 | 2023-12-08 | — | — | CN | claimed |
| WO-2023212494-A2 | PREDICTIVE PESTICIDE RESISTANCE INFORMATION GENERATION AND USE | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2023-11-02 | — | — | WO | claimed |
| EP-3614845-B1 | FUNGICIDAL COMBINATIONS | UPL LTD (IN) | 2023-11-01 | — | — | EP | claimed |
| US-20120283099-A1 | CONTROLLING PLANTHOPPERS | DOW AGROSCIENCES LLC (US) | 2012-11-08 | — | — | US | claimed |
| WO-2012103393-A2 | CONTROLLING MEALYBUGS | DOW AGROSCIENCES LLC (US) | 2012-08-02 | — | — | WO | claimed |
| US-20120195974-A1 | CONTROLLING MEALYBUGS | DOW AGROSCIENCES LLC (US) | 2012-08-02 | — | — | US | claimed |
| WO-2012061290-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-10 | — | — | WO | claimed |
| WO-2012061288-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-10 | — | — | WO | claimed |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | CORTEVA AGRISCIENCE LLC | 2012-05-03 | — | — | US | claimed |
| US-20120110701-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-03 | — | — | US | claimed |
| EP-2323844-A1 | GELATINOUS ELASTOMER COMPOSITIONS | Silipos Inc. (US) | 2011-05-25 | — | — | EP | claimed |
| WO-2010030824-A1 | GELATINOUS ELASTOMER COMPOSITIONS | SILIPOS, INC. (US) | 2010-03-18 | — | — | WO | claimed |
| US-20100063008-A1 | GELATINOUS ELASTOMER COMPOSITIONS | SILIPOS, INC. (US) | 2010-03-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120110701-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, AGPS, DDT | CA2 162/4885CA4 748/4885CES2 511/4885 |
| US-20240138408-A1 | COMPOSITION COMPRISING BENZYLAMINE ACARICIDE AND USE THEREOF | BCHE, AAAS, BROX | CA2 3326/4885CA4 1814/4885CES2 990/4885 |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | ACHE, DDT, PTMS | CA2 210/4885CA4 904/4885CES2 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.