SCHEMBL23833129

SCHEMBL23833129

CC(C)(C)N(C(=O)O)[C@@H](CCC(N)=O)COc1cccc(CCCO)c1Cl

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ADRB2 P07550 16/20 0.33
▸ ADRB1 P08588 11/20 0.33
▸ HTR1D P28221 2/20 0.32
▸ SLC1A5 Q15758 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23833166 0.86 LTB4R (0.33) ADRB2ADRB1SLC1A5
SCHEMBL23833230 0.84 MRGPRX4 (0.39) ADRB2HTR1DSLC1A5
SCHEMBL23833042 0.83 — —
SCHEMBL27015257 0.81 ADRB2 (0.39) ADRB2ADRB1
SCHEMBL27015244 0.79 ADRB2 (0.37) ADRB2ADRB1
SCHEMBL23833241 0.77 AAK1 (0.41) ADRB2ADRB1
SCHEMBL23833128 0.77 AAK1 (0.41) ADRB2ADRB1
SCHEMBL23833328 0.76 — —
SCHEMBL23833333 0.75 AAK1 (0.40) ADRB2ADRB1
SCHEMBL23833330 0.75 AAK1 (0.40) ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016942-A1 STAT DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2024-01-18 — — US disclosed
EP-4121055-A1 STAT DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2023-01-25 — — EP disclosed
WO-2021188696-A1 STAT DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2021-09-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016942-A1 STAT DEGRADERS AND USES THEREOF STAT4, STAT1, STAT3 ADRB2 4571/4885ADRB1 4560/4885HTR1D 4246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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