⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833042 | 0.89 | — | — | |
| SCHEMBL23833166 | 0.86 | LTB4R (0.33) | — | |
| SCHEMBL23833186 | 0.78 | AAK1 (0.40) | — | |
| SCHEMBL23833183 | 0.78 | AAK1 (0.40) | — | |
| SCHEMBL22526798 | 0.77 | MPO (0.36) | — | |
| SCHEMBL23833022 | 0.77 | PKM (0.30) | — | |
| SCHEMBL26206385 | 0.76 | FOS (0.36) | — | |
| SCHEMBL22527096 | 0.76 | MPO (0.36) | — | |
| SCHEMBL23833129 | 0.76 | ADRB2 (0.33) | — | |
| SCHEMBL26206433 | 0.75 | F13A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016942-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
| EP-4121055-A1 | STAT DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021188696-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |