⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833328 | 0.89 | — | — | |
| SCHEMBL23833129 | 0.83 | ADRB2 (0.33) | — | |
| SCHEMBL27015304 | 0.82 | PTGER1 (0.33) | — | |
| SCHEMBL23833166 | 0.79 | LTB4R (0.33) | — | |
| SCHEMBL23833159 | 0.78 | AAK1 (0.42) | — | |
| SCHEMBL23833040 | 0.78 | AAK1 (0.42) | — | |
| SCHEMBL26206444 | 0.75 | PTGER1 (0.36) | — | |
| SCHEMBL23833067 | 0.75 | — | — | |
| SCHEMBL23833230 | 0.73 | MRGPRX4 (0.39) | — | |
| SCHEMBL23832934 | 0.72 | AAK1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016942-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
| EP-4121055-A1 | STAT DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021188696-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |