SCHEMBL23833192

SCHEMBL23833192

CC(C)(C)N(C(=O)O)[C@H](CO)CCC(N)=O

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ PMP22 Q01453 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ DPP4 P27487 1/20 0.32
▸ DPP8 Q6V1X1 1/20 0.32
▸ DPP9 Q86TI2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23833303 1.00 ALOX15 (0.41) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL1024050 0.82 GABRR1 (0.36) —
SCHEMBL16195856 0.81 — —
SCHEMBL14908934 0.80 CHRM1 (0.35) —
SCHEMBL14908935 0.80 CHRM1 (0.35) —
SCHEMBL1024531 0.79 CPB2 (0.42) —
SCHEMBL18342421 0.78 — —
SCHEMBL18342420 0.78 — —
SCHEMBL3726149 0.77 ACACB (0.30) —
SCHEMBL15238859 0.77 CA2 (0.41) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121055-A1 STAT DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2023-01-25 — — EP disclosed
WO-2021188696-A1 STAT DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2021-09-23 — — WO disclosed
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