SCHEMBL49404

SCHEMBL49404

CCC(CC(=O)O)N=C=O

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
FFAR3 O14843 1/20 0.32
GPR84 Q9NQS5 4/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP12 P39900 1/20 0.30
MMP14 P50281 1/20 0.30
MMP15 P51511 1/20 0.30
MMP16 P51512 1/20 0.30
MMP26 Q9NRE1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5126357 0.81 TRPA1 (0.41) SLC22A6TDP1FFAR3GPR84SMN1; SMN2
SCHEMBL49064 0.79 GABRP (0.39) FFAR3MAPT
SCHEMBL332238 0.78
SCHEMBL4122966 0.74
SCHEMBL5172943 0.74
SCHEMBL9057931 0.74
SCHEMBL2383532 0.73
SCHEMBL48787 0.73
SCHEMBL11577897 0.72 SLC22A6 (0.39) SLC22A6TDP1SMN1; SMN2MAPT
SCHEMBL15199822 0.71 SLC22A6 (0.35) SLC22A6TDP1FFAR3GPR84SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284102-A Preparation method of silane coupling agent and application of silane coupling agent in polylactic acid composite material 吉祥三宝高科纺织有限公司 2023-06-23 CN disclosed
WO-2023055427-A1 SMALL MOLECULE ANTAGONISTS OF PF4 NEW YORK BLOOD CENTER, INC. (US) 2023-04-06 WO disclosed
EP-3330252-B1 ISOPRENYL COMPOUNDS AND METHODS THEREOF SIGNUM BIOSCIENCES INC (US) 2020-02-12 EP disclosed
US-10314802-B2 Isoprenyl compounds and methods thereof SIGNUM BIOSCIENCES, INC. (US) 2019-06-11 US disclosed
EP-3330252-A2 ISOPRENYL COMPOUNDS AND METHODS THEREOF Signum Biosciences, Inc. (US) 2018-06-06 EP disclosed
EP-2963012-B1 ISOPRENYL COMPOUNDS AND METHODS THEREOF SIGNUM BIOSCIENCES INC (US) 2018-01-10 EP disclosed
US-20170368011-A1 ISOPRENYL COMPOUNDS AND METHODS THEREOF SIGNUM BIOSCIENCES, INC. (US) 2017-12-28 US disclosed
US-9744147-B2 Isoprenyl compounds and methods thereof SIGNUM BIOSCIENCES, INC. (US) 2017-08-29 US disclosed
US-20160361283-A1 Isoprenyl Compounds and Methods Thereof SIGNUM DERMALOGIX, INC. 2016-12-15 US disclosed
US-9376383-B2 Isoprenyl compounds SIGNUM BIOSCIENCES, INC. (US) 2016-06-28 US disclosed
EP-1866317-A1 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS Pharmacia & Upjohn Company LLC (US) 2007-12-19 EP disclosed
WO-2006103555-A1 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-10-05 WO disclosed
US-20060099417-A1 Polyurethane-based anhydrous sizing compositions for glass fibres, glass fibres obtained and composite materials comprising said fibres SAINT-GOBAIN VETROEX FRANCE (FR) 2006-05-11 US disclosed
US-20050119320-A1 5-phenylthiazole derivatives and use as pi3 kinase inhibitors NOVARTIS AG (CH) 2005-06-02 US disclosed
EP-1480962-A1 5-PHENYLTHIAZOLE DERIVATIVES AND USE AS PI3 KINASE INHIBITORS Novartis AG (CH) 2004-12-01 EP disclosed
EP-0769955-B1 NON-ANTIGENIC AMINE DERIVED POLYMERS AND POLYMER CONJUGATES ENZON INC (US) 2004-03-10 EP disclosed
WO-2003072557-A1 5-PHENYLTHIAZOLE DERIVATIVES AND USE AS PI3 KINASE INHIBITORS NOVARTIS AG (CH) 2003-09-04 WO disclosed
US-6177087-B1 ADMINISTERING A POLYMER CONJUGATE ENZON, INC. 2001-01-23 US disclosed
US-5902588-A Non-antigenic amine derived polymers and polymer conjugates ENZON, INC. (US) 1999-05-11 US disclosed
US-5730990-A Non-antigenic amine derived polymers and polymer conjugates ENZON, INC. (US) 1998-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160361283-A1 Isoprenyl Compounds and Methods Thereof ALOX15B, ALOX15, ALOX5 SLC22A6 3926/4885TDP1 2255/4885FFAR3 889/4885
US-10314802-B2 Isoprenyl compounds and methods thereof ALOX15B, ALOX15, ALOX5 SLC22A6 3926/4885TDP1 2255/4885FFAR3 889/4885
US-20050119320-A1 5-phenylthiazole derivatives and use as pi3 kinase inhibitors PIK3CA, PIK3R5, PIP5K1B SLC22A6 3844/4885TDP1 1723/4885FFAR3 511/4885
US-20170368011-A1 ISOPRENYL COMPOUNDS AND METHODS THEREOF ALOX15B, ALOX15, ALOX5 SLC22A6 3926/4885TDP1 2255/4885FFAR3 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.