Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23837455 | 0.79 | TRPA1 (0.42) | LMNAKMT2ATHRBPOLB | |
| SCHEMBL18966982 | 0.74 | MTNR1A (0.31) | NAMPT | |
| SCHEMBL18966482 | 0.74 | MTNR1A (0.31) | NAMPT | |
| SCHEMBL23837490 | 0.72 | HTR1A (0.34) | LMNADRD2KMT2A | |
| SCHEMBL23837397 | 0.72 | MTNR1A (0.30) | — | |
| SCHEMBL23837583 | 0.70 | TSHR (0.35) | LMNAKMT2APOLB | |
| SCHEMBL18966773 | 0.70 | — | — | |
| SCHEMBL23837493 | 0.69 | MTNR1A (0.33) | DRD2 | |
| SCHEMBL23837563 | 0.69 | MTNR1A (0.37) | LMNAKMT2ATHRB | |
| SCHEMBL23837590 | 0.69 | ALDH1A1 (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882252-A1 | BETA-LACTAMASE INHIBITORS | Venatorx Pharmaceuticals, Inc. (US) | 2021-09-22 | — | — | EP | disclosed |