SCHEMBL8719387

SCHEMBL8719387

Nc1ccc2nc3cc[c]cc3nc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
LMNA P02545 2/20 0.47
HTT P42858 2/20 0.47
F2 P00734 1/20 0.47
CHRM2 P08172 1/20 0.47
HTR1A P08908 1/20 0.47
ADRA2A P08913 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
MAOA P21397 1/20 0.47
DRD1 P21728 1/20 0.47
ACHE P22303 1/20 0.47
PTGS1 P23219 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
OPRM1 P35372 1/20 0.47
DRD3 P35462 1/20 0.47
KDR P35968 1/20 0.47
SLC6A3 Q01959 1/20 0.47
KCNH2 Q12809 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29922808 0.81 KMT2A (0.67) KMT2AMEN1LMNAHTTF2
SCHEMBL3480837 0.81 KMT2A (0.67) KMT2AMEN1LMNAHTTF2
SCHEMBL4586206 0.81 KMT2A (0.67) KMT2AMEN1LMNAHTTF2
Hydrochloric Acid SCHEMBL7566148 0.79 KMT2A (0.64) KMT2AMEN1LMNAHTTF2
SCHEMBL27531134 0.77 MEN1 (0.42) KMT2AMEN1LMNAHTTATM
SCHEMBL27391068 0.77 APAF1 (0.53) KMT2AMEN1ATMKDM4EPOLB
SCHEMBL5803173 0.74 KMT2A (0.67) KMT2AMEN1LMNAHTTF2
SCHEMBL29903456 0.74 KMT2A (0.67) KMT2AMEN1LMNAHTTF2
SCHEMBL23844 0.74 MAPT (0.55) KMT2AMEN1LMNAHTTCHRM2
SCHEMBL6158097 0.69 RAB9A (0.56) KMT2AMEN1LMNAHTTF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0865465-A1 LACCASES WITH IMPROVED DYEING PROPERTIES NOVO NORDISK A/S (DK) 1998-09-23 EP claimed
WO-1997019999-A1 LACCASES WITH IMPROVED DYEING PROPERTIES NOVO NORDISK A/S (DK) 1997-06-05 WO claimed
CN-1167791-C Storage stable liquid formulation comprising a laccase ŵ����÷�����޹�˾ 2004-09-22 CN disclosed
CN-1084357-C Dyeing composition comprising a myceliophthora laccase, use thereof for dyeing keratin fibres and method for dyeing keratin fibres NOVO TJMEIDS AS (DK) 2002-05-08 CN disclosed
CN-1250475-A Storage stable liquid formulation comprising a laccase NOVO NORDISK AS (DK) 2000-04-12 CN disclosed
CN-1203615-A Laccases with improved dyeing properties NOVO NORDISK AS (DK) 1998-12-30 CN disclosed