SCHEMBL15987437

SCHEMBL15987437

[c]1ccc2nc(-c3ccccc3)c(-c3ccccc3)nc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.50
L3MBTL1 Q9Y468 6/20 0.50
LMNA P02545 6/20 0.50
TDP1 Q9NUW8 4/20 0.50
KMT2A Q03164 4/20 0.50
GAA P10253 3/20 0.50
MEN1 O00255 3/20 0.50
ALDH1A1 P00352 8/20 0.47
ATM Q13315 1/20 0.47
TLR9 Q9NR96 1/20 0.47
PKM P14618 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46
THRB P10828 1/20 0.45
HPGD P15428 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
AKT1 P31749 1/20 0.43
AKT2 P31751 1/20 0.43
HTT P42858 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28338278 0.88 KDM4E (0.68) KDM4EL3MBTL1LMNATDP1KMT2A
SCHEMBL714997 0.83 KDM4E (0.59) KDM4EL3MBTL1LMNATDP1KMT2A
SCHEMBL21382895 0.82 KDM4E (0.53) KDM4EL3MBTL1LMNATDP1KMT2A
SCHEMBL17184372 0.81 MAPK14 (0.51) KDM4EL3MBTL1LMNATDP1KMT2A
SCHEMBL23844 0.81 MAPT (0.55) KDM4EL3MBTL1LMNATDP1KMT2A
Water SCHEMBL27680271 0.80 KDM4E (0.71) KDM4EL3MBTL1LMNATDP1KMT2A
SCHEMBL28460776 0.80 KDM4E (0.60) KDM4EL3MBTL1LMNATDP1KMT2A
SCHEMBL29382173 0.78 KDM4E (0.74) KDM4EL3MBTL1LMNATDP1KMT2A
SCHEMBL732131 0.78 KDM4E (0.74) KDM4EL3MBTL1LMNATDP1KMT2A
SCHEMBL5885440 0.77 ALDH1A1 (0.60) KDM4EL3MBTL1LMNATDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4342883-A1 PHOTOELECTRIC CONVERSION ELEMENT MATERIAL FOR IMAGING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING ELEMENT Tosoh Corporation (JP) 2024-03-27 EP disclosed
CN-117440940-A Material for photoelectric conversion element for image pickup element and photoelectric conversion element for image pickup element 东曹株式会社 2024-01-23 CN disclosed
CN-110997648-B Condensed ring compound 东曹株式会社 2023-12-19 CN disclosed
WO-2022260096-A1 PHOTOELECTRIC CONVERSION ELEMENT MATERIAL FOR IMAGING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING ELEMENT 東ソー株式会社 2022-12-15 WO disclosed
CN-110997648-A Fused ring compound 东曹株式会社 2020-04-10 CN disclosed
WO-2019189037-A1 FUSED-RING COMPOUND, METHOD FOR PRODUCING SAME, AND PRODUCTION INTERMEDIATE THEREOF 東ソー株式会社 2019-10-03 WO disclosed
EP-2772483-B1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME TOSOH CORP (JP) 2017-03-29 EP disclosed
US-9172045-B2 4-aminocarbazole compound and use thereof TOSOH CORPORATION (JP) 2015-10-27 US disclosed
US-20140296519-A1 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2014-10-02 US disclosed
EP-2772483-A1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME Tosoh Corporation (JP) 2014-09-03 EP disclosed