Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.46 |
| ▸ | STK25 | O00506 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 4/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | YES1 | P07947 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SPAST | Q9UBP0 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21917834 | 0.65 | GPR84 (0.35) | HCAR3GPR84 | |
| SCHEMBL11520102 | 0.65 | ALDH1A1 (0.56) | ADRB2ADH1BADH1CADH1AADH4 | |
| SCHEMBL11513573 | 0.65 | ALDH1A1 (0.56) | ADRB2ADH1BADH1CADH1AADH4 | |
| SCHEMBL22328204 | 0.65 | MAPK14 (0.41) | STK25NTRK1SPASTMAPK14IGF1R | |
| SCHEMBL39138 | 0.65 | ALDH1A1 (0.56) | ADRB2ADH1BADH1CADH1AADH4 | |
| SCHEMBL1417508 | 0.65 | ALDH1A1 (0.56) | ADRB2ADH1BADH1CADH1AADH4 | |
| SCHEMBL11473790 | 0.65 | ALDH1A1 (0.56) | ADRB2ADH1BADH1CADH1AADH4 | |
| SCHEMBL8886903 | 0.64 | IDO1 (0.39) | ADRB2ADH1BADH1CADH1AADH4 | |
| SCHEMBL1123435 | 0.63 | ADH1B (0.42) | ADRB2ADH1BADH1CADH1AADH4 | |
| SCHEMBL11442419 | 0.63 | ALDH1A1 (0.58) | ADRB2ADH1BADH1CADH1AADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292300-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292300-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | TLR9, TLR7, TLR8 | HCAR3 289/4885STK25 1206/4885ADRB2 1403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.