Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 4/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22527061 | 0.99 | MPO (0.40) | MPOLTB4RLTB4R2ADRB2ADRB1 | |
| SCHEMBL22526193 | 0.87 | ADRB2 (0.41) | MPOADRB2ADRB1SLC6A4HDAC1 | |
| SCHEMBL22527024 | 0.84 | LTB4R (0.36) | MPOLTB4RLTB4R2ADRB2ADRB1 | |
| SCHEMBL26206467 | 0.83 | LTB4R (0.46) | LTB4RLTB4R2ADRB2ADRB1 | |
| SCHEMBL26254335 | 0.82 | MPO (0.38) | MPOLTB4RLTB4R2ADRB2ADRB1 | |
| SCHEMBL26254223 | 0.82 | ADRB2 (0.38) | MPOLTB4RLTB4R2ADRB2ADRB1 | |
| SCHEMBL26206421 | 0.82 | LTB4R (0.44) | MPOLTB4RLTB4R2ADRB2ADRB1 | |
| SCHEMBL27015403 | 0.82 | ADRB2 (0.39) | MPOLTB4RLTB4R2ADRB2ADRB1 | |
| SCHEMBL22527096 | 0.81 | MPO (0.36) | MPOLTB4RLTB4R2SLC6A4S1PR4 | |
| SCHEMBL22527020 | 0.81 | MTNR1A (0.38) | MPOADRB2ADRB1SLC6A4MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188696-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |