SCHEMBL238459

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL240626	0.85	ALDH1A1 (0.44)	KMT2AMAPTMEN1MAPK1LMNA
	SCHEMBL238260	0.85	NPBWR1 (0.43)	VCAM1NPBWR1MCHR1KMT2AMAPT
	SCHEMBL238422	0.85	MAPT (0.37)	VCAM1KMT2AMAPTMEN1KDM4E
	SCHEMBL239628	0.83	KMT2A (0.35)	VCAM1NPBWR1MCHR1KMT2AMAPT
	SCHEMBL238042	0.83	VCAM1 (0.37)	VCAM1NPBWR1MCHR1KMT2AMAPT
	SCHEMBL242322	0.83	KAT2B (0.40)	VCAM1NPBWR1MCHR1KMT2AMAPT
	SCHEMBL242609	0.83	VCAM1 (0.36)	VCAM1NPBWR1MCHR1KMT2AMAPT
	SCHEMBL240192	0.83	KMT2A (0.38)	VCAM1NPBWR1MCHR1KMT2AMAPT
	SCHEMBL241163	0.82	MAPT (0.37)	VCAM1NPBWR1MCHR1KMT2AMAPT
	SCHEMBL240276	0.82	CNR1 (0.39)	VCAM1NPBWR1MCHR1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.