Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.50 |
| ▸ | MPI | P34949 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | PMM2 | O15305 | 5/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.49 |
| ▸ | MIF | P14174 | 4/20 | 0.49 |
| ▸ | PHOSPHO1 | Q8TCT1 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21687129 | 0.87 | MPI (0.63) | MPINPC1RAB9APMM2APOBEC3G | |
| SCHEMBL21687126 | 0.87 | KAT2A (0.64) | SCN4ASCN9AMPINPC1RAB9A | |
| SCHEMBL21687128 | 0.80 | CSNK1D (0.47) | SCN4ASCN9ANPC1RAB9AMIF | |
| SCHEMBL23845934 | 0.78 | SCN4A (0.47) | SCN4ASCN9ANPC1RAB9AMIF | |
| SCHEMBL21687124 | 0.72 | KAT2A (0.68) | MPINPC1RAB9APMM2APOBEC3G | |
| SCHEMBL10489874 | 0.71 | SCN4A (0.57) | SCN4ASCN9ANPC1RAB9ASMN1; SMN2 | |
| Phathalimide SCHEMBL30007061 | 0.71 | SCN4A (0.56) | SCN4ASCN9ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16445277 | 0.69 | SCN4A (0.79) | SCN4ASCN9ANPC1RAB9AAPOBEC3G | |
| SCHEMBL8516006 | 0.67 | SCN4A (1.00) | SCN4ASCN9ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30450972 | 0.67 | ALDH1A1 (0.61) | SCN4ASCN9ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292315-A1 | SELENIUM-CONTAINING ISOXAZOLAMINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | SHANGHAI XINGYE PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292315-A1 | SELENIUM-CONTAINING ISOXAZOLAMINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | AIFM2, GPX1, AIFM1 | SCN4A 1148/4885SCN9A 1731/4885MPI 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.