Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2A | Q92830 | 2/20 | 0.68 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.68 |
| ▸ | G6PD | P11413 | 2/20 | 0.59 |
| ▸ | PMM2 | O15305 | 3/20 | 0.58 |
| ▸ | MPI | P34949 | 3/20 | 0.58 |
| ▸ | SLC11A2 | P49281 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21687126 | 0.85 | KAT2A (0.64) | KAT2AKAT2BG6PDPMM2MPI | |
| SCHEMBL21687129 | 0.85 | MPI (0.63) | KAT2AKAT2BG6PDPMM2MPI | |
| SCHEMBL21687131 | 0.82 | KAT2B (1.00) | KAT2AKAT2BG6PDPMM2MPI | |
| SCHEMBL5916793 | 0.78 | METAP2 (0.57) | SLC11A2MAPTTSHRPKMTDP1 | |
| SCHEMBL21687128 | 0.76 | CSNK1D (0.47) | KAT2AKAT2BSLC11A2MAPTTSHR | |
| SCHEMBL4917268 | 0.75 | CYP1A2 (0.61) | SLC11A2MAPTTSHRPKMTDP1 | |
| SCHEMBL1897990 | 0.75 | G6PD (1.00) | KAT2AKAT2BG6PDPMM2MPI | |
| SCHEMBL2538424 | 0.74 | MPI (1.00) | KAT2BG6PDPMM2MPIMAPT | |
| SCHEMBL8373420 | 0.74 | G6PD (0.80) | G6PDPMM2MPIMAPTPKM | |
| SCHEMBL18845144 | 0.74 | G6PD (0.66) | G6PDPMM2MPIMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292315-A1 | SELENIUM-CONTAINING ISOXAZOLAMINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | SHANGHAI XINGYE PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2021-09-23 | — | — | US | disclosed |
| WO-2020020099-A1 | SELENIUM-CONTAINING ISOXAZOLAMINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海星叶医药科技有限公司 | 2020-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292315-A1 | SELENIUM-CONTAINING ISOXAZOLAMINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | AIFM2, GPX1, AIFM1 | KAT2A 4401/4885KAT2B 4231/4885G6PD 2053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.