Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 8/20 | 0.65 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.51 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.47 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.46 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31314844 | 0.77 | ENPP1 (0.72) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL9039195 | 0.76 | AHCY (0.85) | AHCY | |
| SCHEMBL9040228 | 0.76 | AHCY (0.85) | AHCY | |
| SCHEMBL502621 | 0.72 | ENPP1 (0.52) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL21257339 | 0.72 | P2RX3 (0.53) | ENPP1P2RX1P2RX3P2RX2P2RY2 | |
| SCHEMBL8186426 | 0.72 | AHCY (1.00) | AHCY | |
| SCHEMBL13648201 | 0.72 | ENPP1 (0.65) | AHCYENPP1FGFR1SLC22A6P2RY2 | |
| SCHEMBL18840499 | 0.71 | P2RX3 (0.57) | P2RX1P2RX3P2RX2P2RY2P2RY1 | |
| SCHEMBL25720618 | 0.71 | P2RX1 (0.61) | P2RX1P2RX3P2RX2P2RY2P2RY1 | |
| SCHEMBL1035726 | 0.71 | ENPP1 (0.51) | ENPP1ENPP3P2RX1P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230433-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER | UNIVERSITY OF WASHINGTON (US) | 2011-09-22 | — | — | US | disclosed |