Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23844444 | 0.79 | — | — | |
| SCHEMBL23847680 | 0.78 | DRD2 (0.40) | HTR3AKCNH2GAASMN1; SMN2 | |
| SCHEMBL23844405 | 0.77 | MAPK13 (0.36) | — | |
| SCHEMBL23844397 | 0.75 | HRH4 (0.33) | — | |
| SCHEMBL24239287 | 0.69 | SMYD3 (0.32) | — | |
| SCHEMBL24229664 | 0.69 | LRRK2 (0.34) | — | |
| SCHEMBL24229640 | 0.69 | SMYD3 (0.35) | — | |
| SCHEMBL23847431 | 0.69 | MAPK13 (0.33) | — | |
| SCHEMBL21023585 | 0.68 | GAA (0.41) | HTR3AKCNH2GAASMN1; SMN2 | |
| SCHEMBL30088717 | 0.67 | SIGMAR1 (0.36) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188450-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD (US) | 2021-09-23 | — | — | WO | disclosed |