⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23844405 | 0.85 | MAPK13 (0.36) | — | |
| SCHEMBL23847409 | 0.79 | HTR3A (0.35) | — | |
| SCHEMBL23847431 | 0.77 | MAPK13 (0.33) | — | |
| SCHEMBL23847680 | 0.73 | DRD2 (0.40) | — | |
| SCHEMBL23844397 | 0.71 | HRH4 (0.33) | — | |
| SCHEMBL23844454 | 0.69 | — | — | |
| SCHEMBL24965132 | 0.65 | GRM5 (0.38) | — | |
| SCHEMBL19731837 | 0.61 | MAPK13 (0.30) | — | |
| SCHEMBL26012929 | 0.59 | CYP11B2 (0.30) | — | |
| SCHEMBL25745883 | 0.59 | DRD2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183258-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD | 2023-06-15 | — | — | US | disclosed |
| US-20210292336-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD | 2021-09-23 | — | — | US | disclosed |