Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23847680 | 0.79 | DRD2 (0.40) | KDM5A | |
| SCHEMBL23847409 | 0.75 | HTR3A (0.35) | — | |
| SCHEMBL23844405 | 0.75 | MAPK13 (0.36) | — | |
| SCHEMBL23844444 | 0.71 | — | — | |
| SCHEMBL15071317 | 0.69 | KDM5A (0.36) | HRH4HRH3KDM5A | |
| SCHEMBL17045434 | 0.68 | HRH3 (0.36) | HRH4HRH3 | |
| SCHEMBL23847431 | 0.67 | MAPK13 (0.33) | HRH4 | |
| SCHEMBL24253233 | 0.67 | CCNT1 (0.33) | HRH4HRH3 | |
| SCHEMBL15293676 | 0.67 | HRH3 (0.31) | HRH4HRH3 | |
| SCHEMBL23844433 | 0.66 | HRH4 (0.30) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183258-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD | 2023-06-15 | — | — | US | disclosed |
| US-20210292336-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183258-A1 | NLRP3 MODULATORS | NLRP3, NLRP1, NOD1 | HRH4 2189/4885HRH3 2707/4885KDM5A 4424/4885 |
| US-20210292336-A1 | NLRP3 MODULATORS | NLRP3, NLRP1, NOD1 | HRH4 2189/4885HRH3 2707/4885KDM5A 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.