Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 4/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 4/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2384898 | 0.93 | THRB (0.48) | CNR1CNR2THRBHCAR2HTR1A | |
| SCHEMBL2386952 | 0.93 | THRB (0.48) | CNR1CNR2THRBHCAR2HTR1A | |
| SCHEMBL2384901 | 0.93 | THRB (0.48) | CNR1CNR2THRBHCAR2HTR1A | |
| SCHEMBL2386951 | 0.93 | THRB (0.48) | CNR1CNR2THRBHCAR2HTR1A | |
| (2E)-Hexenoic Acid SCHEMBL2385760 | 0.89 | LTA4H (0.46) | HCAR2HTR1ACYP1A2 | |
| SCHEMBL2385804 | 0.83 | MET (0.52) | CNR1CNR2HTR1A | |
| SCHEMBL2386505 | 0.83 | MET (0.52) | CNR1CNR2HTR1A | |
| SCHEMBL2385802 | 0.83 | MET (0.52) | CNR1CNR2HTR1A | |
| SCHEMBL2386502 | 0.83 | MET (0.52) | CNR1CNR2HTR1A | |
| SCHEMBL8214412 | 0.81 | THRB (0.49) | CNR1CNR2THRBPLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465939-B2 | Aging-related circulating particle-associated lipoprotein B oxidase (apoBNOX) and inhibitors thereof | NOX TECHNOLOGIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-20110217401-A1 | Aging-Related Circulating Particle-Associated Lipoprotein B Oxidase (apoBNOX) and Inhibitors Thereof | NOX TECHNOLOGIES, INC. | 2011-09-08 | — | — | US | disclosed |