Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386952 | 1.00 | THRB (0.48) | THRBCNR1CNR2THRAATM | |
| SCHEMBL2384898 | 1.00 | THRB (0.48) | THRBCNR1CNR2THRAATM | |
| SCHEMBL2386951 | 1.00 | THRB (0.48) | THRBCNR1CNR2THRAATM | |
| (2E)-Hexenoic Acid SCHEMBL2384903 | 0.93 | CNR1 (0.44) | THRBCNR1CNR2THRAHTR1A | |
| SCHEMBL2385802 | 0.89 | MET (0.52) | CNR1CNR2KDM4ECA12CA1 | |
| SCHEMBL2385804 | 0.89 | MET (0.52) | CNR1CNR2KDM4ECA12CA1 | |
| SCHEMBL2386502 | 0.89 | MET (0.52) | CNR1CNR2KDM4ECA12CA1 | |
| SCHEMBL2386505 | 0.89 | MET (0.52) | CNR1CNR2KDM4ECA12CA1 | |
| SCHEMBL2385754 | 0.87 | LTA4H (0.48) | METHTR1A | |
| SCHEMBL2383978 | 0.87 | LTA4H (0.48) | METHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465939-B2 | Aging-related circulating particle-associated lipoprotein B oxidase (apoBNOX) and inhibitors thereof | NOX TECHNOLOGIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-20110217401-A1 | Aging-Related Circulating Particle-Associated Lipoprotein B Oxidase (apoBNOX) and Inhibitors Thereof | NOX TECHNOLOGIES, INC. | 2011-09-08 | — | — | US | disclosed |