SCHEMBL23850

SCHEMBL23850

Cc1cc(N)ccc1Oc1cc(Oc2ccc(N)cc2C)cc(Oc2ccc(N)cc2C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
SMN1; SMN2 Q16637 3/20 0.47
PDE10A Q9Y233 1/20 0.45
MAPT P10636 5/20 0.44
KDM4E B2RXH2 4/20 0.44
LMNA P02545 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
THRB P10828 1/20 0.44
ALOX15 P16050 1/20 0.44
CASP1 P29466 3/20 0.43
TEAD4 Q15561 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
CARM1 Q86X55 2/20 0.39
PRMT6 Q96LA8 2/20 0.39
NR4A1 P22736 1/20 0.39
POLB P06746 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29764012 1.00 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2PDE10AMAPTKDM4E
SCHEMBL311543 0.96 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2PDE10AMAPTKDM4E
SCHEMBL29764079 0.96 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2PDE10AMAPTKDM4E
SCHEMBL20348489 0.92 CASP1 (0.47) ALDH1A1SMN1; SMN2PDE10AMAPTKDM4E
SCHEMBL2992329 0.91 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2PDE10AMAPTKDM4E
SCHEMBL2997554 0.90 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2PDE10AMAPTKDM4E
SCHEMBL31457276 0.89 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2PDE10AMAPTMEN1
SCHEMBL3003478 0.89 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2PDE10AMAPTKDM4E
SCHEMBL29688467 0.89 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2PDE10AMAPTKDM4E
SCHEMBL1155719 0.89 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2PDE10AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230027931-A1 THERMOPLASTIC MOULDING COMPOSITION CONTAINING POLYALKYLENE TEREPHTHALATE BASF SE (DE) 2023-01-26 US disclosed
US-20180006303-A1 ELECTROLYTE MATERIALS FOR USE IN ELECTROCHEMICAL CELLS SION POWER CORPORATION (US) 2018-01-04 US disclosed
EP-2714806-B1 THERMOPLASTIC MOULDING MATERIAL BASF SE (DE) 2015-07-08 EP disclosed
US-8987357-B2 Thermoplastic molding composition BASF SE (DE) 2015-03-24 US disclosed
US-20140045070-A1 ELECTROCHEMICAL CELLS COMPRISING POLYIMIDES BASF SE (DE) 2014-02-13 US disclosed
EP-2609646-A1 ELECTROLYTE MATERIALS FOR USE IN ELECTROCHEMICAL CELLS BASF SE (DE) 2013-07-03 EP disclosed
US-20120302677-A1 THERMOPLASTIC MOLDING COMPOSITION BASF SE (DE) 2012-11-29 US disclosed
WO-2012025543-A1 ELECTROLYTE MATERIALS FOR USE IN ELECTROCHEMICAL CELLS BASF SE (DE) 2012-03-01 WO disclosed
US-8093349-B2 Terminally modified polybranched polyimide, metal-plated terminally modified polybranched polyimide, and method for producing the same UBE INDUSTRIES, LTD. (JP) 2012-01-10 US disclosed
US-20100009206-A1 TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, METAL-PLATED TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, AND METHOD FOR PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-01-14 US disclosed