Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 15/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12833464 | 0.78 | HDAC1 (0.41) | HDAC1HDAC6CXCR4CYP2D6 | |
| SCHEMBL5021376 | 0.78 | P2RX7 (0.45) | HDAC1HDAC6CXCR4CYP2D6 | |
| SCHEMBL10612034 | 0.78 | HDAC1 (0.41) | HDAC1HDAC6CXCR4CYP2D6CHRM3 | |
| SCHEMBL24804097 | 0.78 | HDAC1 (0.41) | HDAC1HDAC6CXCR4CYP2D6 | |
| SCHEMBL2084964 | 0.78 | CXCR4 (0.43) | HDAC1HDAC6CXCR4CYP2D6 | |
| SCHEMBL13857919 | 0.78 | HDAC1 (0.41) | HDAC1HDAC6CXCR4CYP2D6 | |
| SCHEMBL12891529 | 0.78 | CYP2D6 (0.43) | HDAC1HDAC6CXCR4CYP2D6 | |
| SCHEMBL2083952 | 0.78 | CXCR4 (0.43) | HDAC1HDAC6CXCR4CYP2D6 | |
| SCHEMBL12993082 | 0.78 | HDAC1 (0.41) | HDAC1HDAC6CXCR4CYP2D6 | |
| SCHEMBL1514902 | 0.78 | P2RX7 (0.45) | HDAC1HDAC6CXCR4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017541-A1 | INHIBITORS OF ARGINASE | Praxis Biotech LLC | 2022-01-20 | — | — | US | disclosed |
| EP-3883938-A1 | INHIBITORS OF ARGINASE | Praxis Biotech LLC (US) | 2021-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017541-A1 | INHIBITORS OF ARGINASE | ARG1, ARG2, ARGLU1 | HDAC1 132/4885HDAC6 861/4885CXCR4 3523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.