SCHEMBL2385122

SCHEMBL2385122

CCCCNCC(C)(C)CC[SiH2]C(OC)OC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114412 0.83
SCHEMBL1702628 0.78 TSHR (0.41) TSHR
SCHEMBL18456742 0.73 TSHR (0.46) TSHR
SCHEMBL56117 0.72 TSHR (0.41) TSHR
SCHEMBL537902 0.69 ALDH1A1 (0.31) TSHR
SCHEMBL22899107 0.69 TSHR (0.38) TSHR
SCHEMBL3655928 0.69 CA1 (0.31) TSHR
SCHEMBL2388995 0.69 LMNA (0.35) TSHR
SCHEMBL2385119 0.69 TSHR (0.34) TSHR
SCHEMBL57169 0.69 CYP2C19 (0.42) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1981925-B1 HUMIDITY CURING COMPOSITIONS WITH GOOD ADHESION CONTAINING SILANE FUNCTIONAL POLYMERS AND AMINO SILANE ADDUCTS WITH GOOD ADHESION SIKA TECH AG (CH) 2017-08-02 EP disclosed
US-8012302-B2 Moisture-curing compositions containing silane-functional polymers and aminosilane adducts with good adhesive properties SIKA TECHNOLOGY AG (CH) 2011-09-06 US disclosed
EP-1717240-B1 Organoalkoxysilanes for use in moisture curable compositions SIKA TECHNOLOGY AG (CH) 2010-09-22 EP disclosed
US-20090081470-A1 Moisture-Curing Compositions Containing Silane-Functional Polymers and Aminosilane Adducts With Good Adhesive Properties SIKA TECHNOLOGY AG (CH) 2009-03-26 US disclosed
US-20090075096-A1 Organoalkoxysilanes SIKA TECHNOLOGY AG (CH) 2009-03-19 US disclosed
EP-1981925-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS AND AMINOSILANE ADDUCTS WITH GOOD ADHESIVE PROPERTIES Sika Technology AG (CH) 2008-10-22 EP disclosed
WO-2007085622-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS AND AMINOSILANE ADDUCTS WITH GOOD ADHESIVE PROPERTIES SIKA TECHNOLOGY AG (CH) 2007-08-02 WO disclosed
US-20070055038-A1 Adducts containing isocyanate groups and composition adhering effectively to painted substrates SIKA TECHNOLOGY AG (CH) 2007-03-08 US disclosed
EP-1760100-A1 Isocyanate group containing adducts and compositions having good adhesion on coated substrates Sika Technology AG (CH) 2007-03-07 EP disclosed
CN-1923804-A Adducts containing isocyanate groups and composition adhering effectively to painted substrates SIKA TECHNOLOGY AG (CH) 2007-03-07 CN disclosed
EP-1717240-A1 Organoalkoxysilanes for use in moisture curable compositions Sika Technology AG (CH) 2006-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090075096-A1 Organoalkoxysilanes CDH1, TST, EPCAM TSHR 3707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.