Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23852402 | 1.00 | F2RL1 (0.33) | F2RL1KDM4CNPC1RAB9AADRA1A | |
| SCHEMBL25010943 | 1.00 | F2RL1 (0.33) | F2RL1KDM4CNPC1RAB9AADRA1A | |
| SCHEMBL30223713 | 0.88 | MEN1 (0.31) | KDM4CNPC1RAB9A | |
| SCHEMBL25011314 | 0.80 | F2RL1 (0.32) | F2RL1 | |
| SCHEMBL31589707 | 0.77 | — | — | |
| SCHEMBL23851287 | 0.77 | KDM4C (0.33) | KDM4CNPC1RAB9A | |
| SCHEMBL23851286 | 0.77 | KDM4C (0.33) | KDM4CNPC1RAB9A | |
| SCHEMBL5867597 | 0.75 | F2RL1 (0.36) | F2RL1ADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL8123850 | 0.74 | SLC6A3 (0.39) | ADRA1A | |
| SCHEMBL29757580 | 0.72 | CYP19A1 (0.40) | KDM4CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092055-A1 | Aromatic Acetylene Derivative, Preparation Method Therefor, And Pharmaceutical Use Thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2026-04-02 | — | — | US | disclosed |
| US-20240382465-A1 | AROMATIC ACETYLENE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2024-11-21 | — | — | US | disclosed |
| WO-2024153173-A1 | AROMATIC ACETYLENE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-07-25 | — | — | WO | disclosed |
| EP-4382527-A1 | AROMATIC ACETYLENE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2024-06-12 | — | — | EP | disclosed |
| US-20240166609-A1 | ANTIBACTERIAL COMPOUNDS | BLACKSMITH MEDICINES, INC. | 2024-05-23 | — | — | US | disclosed |
| US-20240150298-A1 | ANTIBACTERIAL COMPOUNDS | BLACKSMITH MEDICINES, INC. | 2024-05-09 | — | — | US | disclosed |
| WO-2024083177-A1 | AROMATIC ACETYLENE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 浙江海正药业股份有限公司 | 2024-04-25 | — | — | WO | disclosed |
| WO-2024067812-A1 | AROMATIC ACETYLENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-04-04 | — | — | WO | disclosed |
| WO-2024067813-A1 | AROMATIC ACETYLENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 浙江海正药业股份有限公司 | 2024-04-04 | — | — | WO | disclosed |
| CN-117769548-A | Aromatic acetylene derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117279897-A | Antibacterial compounds | 布莱克史密斯医药公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-117279898-A | Antibacterial compounds | 布莱克史密斯医药公司 | 2023-12-22 | — | — | CN | disclosed |
| WO-2023011574-A1 | AROMATIC ACETYLENE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-02-09 | — | — | WO | disclosed |
| US-20220002279-A1 | NOVEL IMIDAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2022-01-06 | — | — | US | disclosed |
| EP-3884940-A1 | NOVEL IMIDAZOLE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2021-09-29 | — | — | EP | disclosed |
| CN-112996505-A | Novel imidazole derivatives | 大正制药株式会社 | 2021-06-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166609-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, MPO, RPN2 | F2RL1 3697/4885KDM4C 3976/4885NPC1 1934/4885 |
| US-20240382465-A1 | AROMATIC ACETYLENE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | FAR1, ACAD11, ACOX1 | F2RL1 2953/4885KDM4C 1678/4885NPC1 200/4885 |
| US-20220002279-A1 | NOVEL IMIDAZOLE DERIVATIVE | SLC11A2, MLX, LPXN | F2RL1 2048/4885KDM4C 506/4885NPC1 1858/4885 |
| US-20260092055-A1 | Aromatic Acetylene Derivative, Preparation Method Therefor, And Pharmaceutical Use Thereof | LPXN, AGXT, FAR1 | F2RL1 3291/4885KDM4C 1154/4885NPC1 132/4885 |
| US-20240150298-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, MPO, RPN2 | F2RL1 3697/4885KDM4C 3976/4885NPC1 1934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.