Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23851488 | 0.78 | ALDH1A1 (0.48) | RXFP1SIGMAR1ALDH1A1POLBLMNA | |
| SCHEMBL30237082 | 0.77 | SIGMAR1 (0.41) | RXFP1SIGMAR1ALDH1A1POLBTPSAB1 | |
| SCHEMBL23850969 | 0.75 | RXFP1 (0.39) | RXFP1SIGMAR1ALDH1A1TPSAB1TPSD1 | |
| SCHEMBL17293693 | 0.75 | ALDH1A1 (0.45) | RXFP1ALDH1A1POLBTPSAB1TPSD1 | |
| SCHEMBL17978906 | 0.72 | HRH3 (0.40) | SIGMAR1ALDH1A1TPSAB1TPSD1TPSG1 | |
| SCHEMBL26633220 | 0.72 | SCN9A (0.52) | SIGMAR1TPSAB1TPSD1TPSG1SCN5A | |
| SCHEMBL25315094 | 0.72 | HRH3 (0.40) | SIGMAR1ALDH1A1POLBTPSAB1TPSD1 | |
| SCHEMBL18399136 | 0.72 | LMNA (0.36) | RXFP1ALDH1A1POLBHSP90AA1LMNA | |
| SCHEMBL27627299 | 0.72 | ALDH1A1 (0.56) | ALDH1A1POLBLMNASCN5ASCN2A | |
| SCHEMBL19717800 | 0.72 | SCN7A (0.47) | RXFP1SIGMAR1ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359403-A1 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BeiGene Switzerland GmbH (CH) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022268052-A9 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023125908-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |
| WO-2022268052-A1 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BEIGENE, LTD. (KY) | 2022-12-29 | — | — | WO | disclosed |
| EP-3883928-A1 | GLP-1R AGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2021-09-29 | — | — | EP | disclosed |