Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | FRK | P42685 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23853847 | 0.87 | MAP4K4 (0.38) | MAP4K4EGFRPRKACAFRKMAPK9 | |
| SCHEMBL30149424 | 0.76 | PRMT5 (0.40) | CPT1AGLP1RCPT2 | |
| SCHEMBL15645841 | 0.70 | CPT1A (0.40) | GRM5PRCPKDM5ACPT1ALMNA | |
| SCHEMBL31306872 | 0.70 | LMNA (0.47) | MEN1LMNAMAPTTSHRHTT | |
| SCHEMBL28292819 | 0.69 | CPT1A (0.42) | GRM5PRCPKDM5ACPT1ACPT2 | |
| SCHEMBL31306936 | 0.68 | TSHR (0.47) | MEN1LMNAMAPTTSHRHTT | |
| SCHEMBL25436212 | 0.64 | CPT1A (0.42) | CPT1ACXCR3HPDCPT2PTGER1 | |
| SCHEMBL29108723 | 0.64 | MAP4K4 (0.36) | MAP4K4EGFRPRKACAFRKMAPK9 | |
| SCHEMBL30745343 | 0.64 | TSHR (0.44) | MEN1LMNAMAPTTSHRHTT | |
| SCHEMBL22391791 | 0.62 | TRPV3 (0.47) | MAPTNPSR1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883928-A1 | GLP-1R AGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2021-09-29 | — | — | EP | disclosed |