Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26962967 | 0.84 | HRH3 (0.67) | HRH3 | |
| Trifluoroacetic Acid SCHEMBL1920766 | 0.84 | SIGMAR1 (0.53) | DPP8 | |
| Trifluoroacetic Acid SCHEMBL2267986 | 0.83 | SIGMAR1 (0.57) | HRH3MEN1KMT2AATM | |
| Trifluoroacetic Acid SCHEMBL2267982 | 0.83 | SIGMAR1 (0.57) | HRH3MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL23850153 | 0.82 | HRH3 (0.64) | HRH3 | |
| Trifluoroacetic Acid SCHEMBL2269036 | 0.82 | ALDH1A1 (0.57) | HRH3MEN1KMT2ADPP7 | |
| SCHEMBL5319459 | 0.80 | HRH3 (0.74) | HRH3 | |
| SCHEMBL1505875 | 0.79 | HRH3 (0.78) | HRH3 | |
| SCHEMBL6731656 | 0.79 | HRH3 (0.78) | HRH3 | |
| Benzoic Acid SCHEMBL9768303 | 0.77 | CYP2D6 (0.62) | HRH3MEN1KMT2AATMFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883925-A1 | CYCLIC UREAS | Sironax Ltd (KY) | 2021-09-29 | — | — | EP | disclosed |