Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2267986 | 1.00 | SIGMAR1 (0.57) | SIGMAR1ALDH1A1KMT2ALMNAMEN1 | |
| Trifluoroacetic Acid SCHEMBL2269036 | 0.98 | ALDH1A1 (0.57) | SIGMAR1ALDH1A1KMT2ALMNAMEN1 | |
| Trifluoroacetic Acid SCHEMBL2267366 | 0.85 | KCNJ1 (0.67) | SIGMAR1ALDH1A1KMT2ALMNATSHR | |
| Bicarbonate SCHEMBL28225544 | 0.84 | ALDH1A1 (0.64) | SIGMAR1ALDH1A1KMT2AMEN1TSHR | |
| Carbamic Acid SCHEMBL6249677 | 0.84 | TSHR (0.63) | SIGMAR1ALDH1A1KMT2ALMNAMEN1 | |
| Trifluoroacetic Acid SCHEMBL23853580 | 0.83 | HRH3 (0.57) | KMT2AMEN1HRH3ATM | |
| SCHEMBL13952 | 0.83 | SIGMAR1 (0.81) | SIGMAR1ALDH1A1LMNAHRH3CYP2D6 | |
| SCHEMBL1777747 | 0.83 | SIGMAR1 (0.81) | SIGMAR1ALDH1A1LMNAHRH3CYP2D6 | |
| Acetic Acid SCHEMBL7594626 | 0.82 | ALDH1A1 (0.62) | SIGMAR1ALDH1A1KMT2AMEN1TSHR | |
| 1-Phenethylpiperidine SCHEMBL14734798 | 0.82 | SIGMAR1 (0.72) | SIGMAR1ALDH1A1KMT2AMEN1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201657-A1 | AMIDE SUBSTITUTED INDAZOLE AND BENZOTRIAZOLE DERIVATIVES AS POLY(ADP-RIBOSE)POLYMERASE (PARP) INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201657-A1 | AMIDE SUBSTITUTED INDAZOLE AND BENZOTRIAZOLE DERIVATIVES AS POLY(ADP-RIBOSE)POLYMERASE (PARP) INHIBITORS | PARP1, PARP3, PARP2 | SIGMAR1 4561/4885ALDH1A1 325/4885KMT2A 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.