Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | PRNP | P04156 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24088169 | 0.85 | ACMSD (0.58) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23850126 | 0.76 | ACMSD (0.52) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23853860 | 0.75 | MAPT (0.41) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23850128 | 0.73 | ACMSD (0.78) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23853862 | 0.70 | ACMSD (0.47) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL24088170 | 0.70 | ACMSD (0.55) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL27629133 | 0.64 | L3MBTL1 (0.41) | ALDH1A1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL1691249 | 0.64 | L3MBTL1 (0.43) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL27848979 | 0.63 | F10 (0.42) | ALDH1A1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL27484846 | 0.62 | HDAC1 (0.50) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883930-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | Tes Pharma S.r.l. (IT) | 2021-09-29 | — | — | EP | disclosed |