Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23853862 | 0.81 | ACMSD (0.47) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL23850126 | 0.80 | ACMSD (0.52) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL23853864 | 0.75 | ALDH1A1 (0.42) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL24088169 | 0.70 | ACMSD (0.58) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL24088170 | 0.68 | ACMSD (0.55) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL23850128 | 0.67 | ACMSD (0.78) | MAPTMEN1KMT2ANPSR1RXFP1 | |
| SCHEMBL27484846 | 0.63 | HDAC1 (0.50) | MAPTMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL2082661 | 0.63 | MAPK14 (0.47) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL1691249 | 0.63 | L3MBTL1 (0.43) | MAPTMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL30088453 | 0.62 | PDCD1 (0.54) | RXFP1LMNAALOX15GLAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883930-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | Tes Pharma S.r.l. (IT) | 2021-09-29 | — | — | EP | disclosed |