SCHEMBL23854833

SCHEMBL23854833

C[CH]c1cccc2c1C=CC2

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28757237 0.80 CA1 (0.30) CA1CA2
SCHEMBL7636146 0.80 ALDH1A1 (0.34) CA1CA2
SCHEMBL2860485 0.80 MEN1 (0.41) CA1CA2
SCHEMBL29561529 0.80 MEN1 (0.41) CA1CA2
SCHEMBL22669111 0.74
SCHEMBL6533122 0.74 NFE2L2 (0.47)
SCHEMBL8766117 0.72 CA1 (0.32) CA1CA2
SCHEMBL319418 0.72 CYP2A6 (0.35) CA1CA2
SCHEMBL6454972 0.71 CA1 (0.35) CA1CA2
SCHEMBL277191 0.70 CA1 (0.33) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113831392-A Method for producing drug-related peptides 康德生物医疗技术公司 2021-12-24 CN disclosed
CN-107530395-B Method for producing drug-related peptides 康德生物医疗技术公司 2021-10-22 CN disclosed
US-20210300872-A1 SECOND GENERATION GRP94-SELECTIVE INHIBITORS UNIVERSITY OF KANSAS 2021-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210300872-A1 SECOND GENERATION GRP94-SELECTIVE INHIBITORS HSP90B1, HSP90AB2P, HSPE1 CA1 3313/4885CA2 1143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.