Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019488 | 0.85 | PTGS2 (0.36) | CYP3A4CYP2C9PTGS2LMNASMN1; SMN2 | |
| SCHEMBL5690313 | 0.77 | BRD4 (0.38) | PTAFRBRD4CREBBPTP53LMNA | |
| SCHEMBL3065043 | 0.74 | HRH3 (0.37) | BRD4CREBBPCYP2C9SMN1; SMN2RAB9A | |
| SCHEMBL5689983 | 0.74 | BRD4 (0.36) | PTAFRBRD4CREBBPTP53LMNA | |
| SCHEMBL4471130 | 0.73 | PTAFR (0.37) | PTAFRBRD4CREBBPCYP3A4CYP2C9 | |
| SCHEMBL4469495 | 0.72 | PTAFR (0.38) | PTAFRBRD4CREBBPCYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL5690129 | 0.70 | PTGS2 (0.35) | BRD4CREBBPCYP3A4CYP2C9PTGS2 | |
| Hydrochloric Acid SCHEMBL6892675 | 0.69 | PTGS2 (0.35) | BRD4CREBBPCYP3A4CYP2C9PTGS2 | |
| SCHEMBL27199723 | 0.69 | TSHR (0.37) | PTAFRBRD4CREBBPTP53LMNA | |
| Hydrochloric Acid SCHEMBL6886337 | 0.68 | PTGS2 (0.34) | BRD4CREBBPCYP3A4CYP2C9PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101889030-B | Metallocene compound, catalyst containing the same, and process for producing olefin polymer using the catalyst | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2013-07-17 | — | — | CN | disclosed |
| US-8415492-B2 | Metallocene compounds, catalysts comprising them, process for producing an olefin polymer by use of the catalysts, and olefin homo- and copolymers | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2013-04-09 | — | — | US | disclosed |
| EP-2384343-A1 | NEW METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS | Lummus Novolen Technology Gmbh (DE) | 2011-11-09 | — | — | EP | disclosed |
| US-20110230630-A1 | METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2011-09-22 | — | — | US | disclosed |
| CN-101889030-A | Metallocene compound, catalyst containing the same, process for producing olefin polymer using the catalyst, and olefin homopolymer and copolymer | NOVOLEN TECH HOLDINGS CV | 2010-11-17 | — | — | CN | disclosed |
| WO-2010077230-A1 | NEW METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230630-A1 | METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS | PIN1, PCNA, OPRM1 | PTAFR 2233/4885BRD4 453/4885CREBBP 3229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.