Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | PTPRF | P10586 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2385863 | 0.85 | PTAFR (0.36) | PTGS2NPSR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3065043 | 0.82 | HRH3 (0.37) | POLBMAPTALDH1A1PTPN1PTPRC | |
| SCHEMBL4476579 | 0.70 | CHRNB2 (0.57) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| SCHEMBL28816105 | 0.70 | CHRNB2 (0.57) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| SCHEMBL8151002 | 0.70 | ALDH1A1 (0.50) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| SCHEMBL31597244 | 0.70 | CXCR5 (0.42) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| Phosphine SCHEMBL2085260 | 0.69 | CHRNB2 (0.59) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| SCHEMBL27995875 | 0.68 | CHRNB2 (0.58) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| SCHEMBL4467167 | 0.68 | POLB (0.37) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| SCHEMBL16115092 | 0.67 | CHRNB2 (0.39) | PTGS2CHRNB2CHRNA4POLBCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102964371-B | A kind of preparation method of silicon bridge vicinal resistance type cyclopentadiene compounds | SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2015-08-12 | — | — | CN | disclosed |