SCHEMBL241107

SCHEMBL241107

C[C@@H](NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NCC(=O)NC([C]=O)Cc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 16/20 0.74
OPRM1 P35372 9/20 0.74
OPRK1 P41145 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL238636 1.00 OPRD1 (0.74) OPRD1OPRM1OPRK1
SCHEMBL2191632 0.89 OPRD1 (0.61) OPRD1OPRM1OPRK1
SCHEMBL11286107 0.87 OPRD1 (0.61) OPRD1OPRM1OPRK1
SCHEMBL29721310 0.85 OPRD1 (0.77) OPRD1OPRM1OPRK1
SCHEMBL11246910 0.85 OPRD1 (0.77) OPRD1OPRM1OPRK1
SCHEMBL29549215 0.85 OPRD1 (0.88) OPRD1OPRM1OPRK1
Biphalin SCHEMBL29582936 0.85 OPRD1 (1.00) OPRD1OPRM1OPRK1
SCHEMBL11053897 0.85 OPRD1 (0.88) OPRD1OPRM1OPRK1
SCHEMBL8893265 0.84 CTSC (0.67) OPRD1OPRM1OPRK1
SCHEMBL9143188 0.84 CTSC (0.67) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8877891-B2 Method of producing a novel opioid peptide LIPKOWSKI ANDREJ (PL) 2014-11-04 US disclosed
US-20120004180-A1 METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE LIPKOWSKI ANDREJ (PL) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004180-A1 METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE OPRL1, OPRK1, OGFR OPRD1 5/4885OPRM1 4/4885OPRK1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.