Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864623 | 0.85 | ALDH1A1 (0.49) | POLBNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23864215 | 0.83 | POLB (0.44) | POLBNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23864747 | 0.82 | CTRC (0.45) | POLBTHRATHRBKCNK2 | |
| SCHEMBL23864449 | 0.80 | ALDH1A1 (0.49) | POLBNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23864195 | 0.78 | ALOX15 (0.41) | POLBNPC1RAB9AHPGDALOX15 | |
| SCHEMBL23864155 | 0.78 | CTRC (0.49) | THRATHRBCA1CA2 | |
| SCHEMBL16088656 | 0.75 | TRPV1 (0.53) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16088663 | 0.75 | TRPV1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1KCNK2 | |
| SCHEMBL23864295 | 0.72 | POLB (0.46) | POLBNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23864512 | 0.72 | ITGB1 (0.52) | POLBNPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |