Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SELL | P14151 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864722 | 0.84 | ALDH1A1 (0.40) | PYGLPTGER4PTGER2KMT2AALDH1A1 | |
| SCHEMBL23864361 | 0.81 | PLA2G1B (0.36) | PYGLPTGER4PTGER2KMT2AALDH1A1 | |
| SCHEMBL16088672 | 0.80 | PTGER4 (0.63) | PYGLPTGER4PTGER2KMT2ANR1H4 | |
| SCHEMBL23864209 | 0.80 | PTGER4 (0.51) | PYGLPTGER4PTGER2KMT2ANR1H4 | |
| SCHEMBL16127851 | 0.78 | PTGER4 (0.67) | PYGLPTGER4PTGER2KMT2ANR1H4 | |
| SCHEMBL16127850 | 0.78 | PTGER4 (0.67) | PYGLPTGER4PTGER2KMT2ANR1H4 | |
| SCHEMBL16088644 | 0.74 | KMT2A (0.60) | PYGLPTGER4PTGER2KMT2ANR1H4 | |
| SCHEMBL24735197 | 0.72 | PTGER4 (0.74) | PYGLPTGER4PTGER2NR1H4ALDH1A1 | |
| SCHEMBL29404059 | 0.72 | PTGER4 (0.74) | PYGLPTGER4PTGER2NR1H4ALDH1A1 | |
| SCHEMBL22113967 | 0.71 | PTGER4 (0.62) | PYGLPTGER4PTGER2KMT2ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |