Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864209 | 0.86 | PTGER4 (0.51) | ALDH1A1PYGLPTGER4PTGER2LMNA | |
| SCHEMBL23864490 | 0.84 | KMT2A (0.36) | ALDH1A1KMT2AKDM4EHTTTP53 | |
| SCHEMBL23864280 | 0.84 | PYGL (0.53) | ALDH1A1PYGLPTGER4PTGER2LMNA | |
| SCHEMBL23864361 | 0.80 | PLA2G1B (0.36) | ALDH1A1PYGLPTGER4PTGER2PLA2G1B | |
| SCHEMBL23864435 | 0.77 | KMT2A (0.38) | ALDH1A1KMT2AHTTTP53 | |
| SCHEMBL23864571 | 0.76 | SMN1; SMN2 (0.39) | ALDH1A1LMNAKMT2AHPGDKDM4E | |
| SCHEMBL23864341 | 0.76 | KMT2A (0.40) | ALDH1A1LMNAKMT2AKDM4EHTT | |
| SCHEMBL21207989 | 0.73 | CES2 (0.41) | ALDH1A1 | |
| SCHEMBL23864723 | 0.69 | MAPT (0.37) | ALDH1A1LMNAKMT2AHPGDMEN1 | |
| SCHEMBL23864221 | 0.69 | TXNRD1 (0.38) | ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |