Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22113949 | 0.82 | HTT (0.54) | HTT | |
| SCHEMBL16127886 | 0.82 | HTT (0.69) | HTT | |
| SCHEMBL23864721 | 0.78 | ACLY (0.47) | HTTGRM5 | |
| SCHEMBL2255814 | 0.74 | ALDH1A1 (0.59) | HTT | |
| SCHEMBL23864625 | 0.72 | TAS2R14 (0.55) | — | |
| SCHEMBL23864342 | 0.71 | KMT2A (0.44) | HTT | |
| SCHEMBL28284734 | 0.71 | GPR35 (0.56) | — | |
| SCHEMBL26264835 | 0.70 | TMPRSS4 (0.46) | HTT | |
| SCHEMBL31626542 | 0.70 | TMPRSS4 (0.46) | HTT | |
| SCHEMBL3551683 | 0.70 | GPR35 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |