Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | PPM1D | O15297 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14452916 | 0.72 | PRSS1 (0.52) | HSD17B10 | |
| SCHEMBL30343750 | 0.71 | HSD17B10 (0.55) | HSD17B10ALDH1A1POLBHPGDCTDSP1 | |
| SCHEMBL2260448 | 0.71 | SMN1; SMN2 (0.38) | MAOAMAOBHSD17B10HPGDL3MBTL1 | |
| SCHEMBL20274421 | 0.70 | KDM4E (0.48) | MAOAMAOBHSD17B10ALDH1A1POLB | |
| SCHEMBL20072018 | 0.70 | TSHR (0.45) | HSD17B10ALDH1A1POLBHPGDL3MBTL1 | |
| SCHEMBL16795534 | 0.68 | HDAC8 (0.60) | MAOAMAOBALDH1A1L3MBTL1HDAC6 | |
| SCHEMBL7102004 | 0.67 | MAOA (0.41) | MAOAMAOBHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL23864748 | 0.67 | NR1H4 (0.40) | ALDH1A1POLBL3MBTL1 | |
| SCHEMBL27446020 | 0.66 | CASP3 (0.35) | MAOAMAOBHSD17B10ALDH1A1POLB | |
| SCHEMBL15832195 | 0.66 | ROCK2 (0.40) | MAOAMAOBHPGDL3MBTL1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |